Abstract: Intramuscular myxoma is a rare benign soft tissue tumor with unclear etiology and histology. Typically occurring in the heart and rarely in the musculoskeletal system, it presents as a relatively clear lesion with a clinical diagnosis tending towards benignity. We report a case of a 74-year-old male with swelling and pain in the left leg, diagnosed via MRI with a characteristic cystic mass in the flexor hallucis longus muscle. Histopathological examination revealed typical features of myxoma, including low signal intensity on T1-weighted imaging and high signal intensity on T2-weighted imaging, consistent with a mucus-rich tumor stroma.
