Abstract: Knee osteoarthritis (OA) is a usual problem in the elderly population, which is treated with lifestyle modifications, non-steroidal anti-inflammatory drugs, physiotherapy, and intraarticular injections of corticosteroids/hyaluronic acid/autologous platelet-rich plasma (PRP) in the early stages, and in the late stages, surgical procedures, such as arthroscopic debridement, unicompartmental arthroplasty, patellofemoral arthroplasty, and total knee replacement, are performed. Gradually, there is an increasing trend in the use of intraarticular autologous PRP for treatment of Kellgren Lawrence grade 1 and 2 knee OA. This prospective study aimed to assess the functional outcome of patients with OA when treated with autologous intraarticular PRP for a follow-up period of up to 15 months.
This study included 40 individuals with Kellgren Lawrence grade 1 and 2 knee OA who were aged 50–70 years and treated with single autologous intraarticular PRP injection and followed at 1, 3, 6, 12, and 15 months after injection, and visual analog scale (VAS) score was calculated at each follow-up.
Preprocedure VAS score of all patients was obtained as 100 mm, and the VAS score was calculated at follow-up on 1, 3, 6, 12, and 15 months and ranged from 13 to 45.
